| Descriptor English: | Lim Kinases | ||||||
| Descriptor Spanish: |
Quinasas Lim
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| Descriptor Portuguese: | Quinases Lim | ||||||
| Descriptor French: | Lim Kinases | ||||||
| Entry term(s): |
Kinase, LIM Kinases, Lim LIM Kinase LIM Motif Containing Protein Kinases LIM Motif-Containing Protein Kinases LIM-Kinase |
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| Tree number(s): |
D08.811.913.696.620.682.700.542 D12.776.476.563.542 D12.776.512.124 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D054461 | ||||||
| Scope note: | Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.1 | ||||||
| Public MeSH Note: | 2008; LIM KINASES was indexed under PROTEIN KINASES 1995-2007 |
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| History Note: | 2008 |
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| DeCS ID: | 52744 | ||||||
| Unique ID: | D054461 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2008/01/01 | ||||||
| Date of Entry: | 2007/07/09 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Lim Kinases
- Preferred
| Concept UI |
M0242922 |
| Scope note | Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE. |
| Preferred term | Lim Kinases |
| Entry term(s) |
Kinase, LIM Kinases, Lim LIM Kinase LIM Motif Containing Protein Kinases LIM Motif-Containing Protein Kinases LIM-Kinase |
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